• Login or Create Account

You are booking hotel for more than 30 days

111 Properties in South Main, Houston (TX), Texas

Sort By:
  • Popular
  • User Rating (Highest First)
  • Price (Highest First)
  • Price (Lowest First)
Hotels in South Main, Houston (TX), Texas are very affordable and a good option for staying in case you are planning a visit to Houston (TX), Texas. Below are some of the best hotels in South Main, Houston (TX), Texas offered by us for you to choose from. The rooms are very clean and comfortable with high-class amenities being provided to the guests. Book one from the below list of Houston (TX), Texas Hotels in South Main, Houston (TX), Texas at the best prices, starting from 177. Explore & book to grab exclusive deals and discounts now. Get Up to 20% (up to AED 400) Off* on hotel booking in Houston (TX), Texas with MakeMyTrip using coupon code : “SUPERSAVER” valid on 100,000+ Hotels. View More
map
Applied FiltersClear

South Main, Houston (TX), Texas

Select Filters

Prices and Budget
  • (1)
  • (4)
  • (9)
  • (2)
  • (4)
  • (1)

Your Budget

to
Star Category
  • (11)
User Rating
  • (3)
  • (4)
  • (8)
  • (1)
  • (1)
Property Type
  • (82)
  • (19)
  • (8)

Show 1 more

Locality

Popular locations

Chains
  • (2)
  • (2)
Amenities
Guests Love
  • (78)
  • (90)

Show -2 more

Booking Preference
Booking Preference
  • (80)
  • (110)
  • (91)
BACK TO TOP

hotelImg
default background imagedefault background imagedefault background imagedefault background image

Residence Inn by Marriott Houston Medical Center/NRG Park

Astrodome | In South Main, Houston (TX), Texas
Studio, Multiple Beds, Non Smoking, City View (mobility Accessible, Tub)
| Queenbed
GymGym
Elevator/LiftElevator/Lift
Free Cancellation
Book @ AED 0
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.6

Based on 406 Ratings and 0 reviews

Cleanliness4.7

Room4.7

Hospitality4.6

(406 Ratings)

AED 1,870

+ AED 368 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Staybridge Suites Houston - Medical Center

Braeswood Place | In South Main, Houston (TX), Texas
Studio Ste 1 Qn Hearing Accessible Nosmk
| Queen Bed
GymGym
Elevator/LiftElevator/Lift
Free ParkingFree Parking
Free Cancellation
Book @ AED 0
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.4

Based on 648 Ratings and 0 reviews

Cleanliness4.5

Room4.5

Hospitality4.5

(648 Ratings)

AED 1,356

+ AED 230 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Comfort Suites near Texas Medical Center - NRG Stadium

Braeswood Place | In South Main, Houston (TX), Texas
Suite, 1 King Bed With Sofa Bed, Non Smoking
| Kingbed
Swimming PoolSwimming Pool
GymGym
Elevator/LiftElevator/Lift
Free Cancellation till 24 hrs before check in
Book @ AED 0
Breakfast Included
Hurry! only last few rooms left at this price
Excellent4.3

Based on 747 Ratings and 0 reviews

Location4.5

Cleanliness4.4

Room4.2

Hospitality4.4

Value For Money4

(747 Ratings)

AED 1,021

AED 853

+ AED 224 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Hotel Ylem

Braeswood Place | In South Main, Houston (TX), Texas
Standard Room, 1 King Bed, Non Smoking
| Kingbed
Free Shuttle ServiceFree Shuttle Service
GymGym
BarBar
Book @ AED 0
Breakfast Included
Very Good4.2

Based on 1776 Ratings and 0 reviews

Location4.8

Cleanliness4.2

Room4.1

Hospitality4.3

(1776 Ratings)

AED 531

AED 456

+ AED 135 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Americas Best Value Inn NRG Park Medical Center

Braeswood Place | In South Main, Houston (TX), Texas
Double King Bed Non Smoking
| King-size Bed 150-183 Width
Free Shuttle ServiceFree Shuttle Service
Swimming PoolSwimming Pool
BarBar
Free Cancellation
Book @ AED 0

AED 387

AED 312

+ AED 97 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Holiday Inn Express & Suites Houston Medical Center

South Main
Standard Room, 1 King Bed
| Kingbed
Swimming PoolSwimming Pool
GymGym
Elevator/LiftElevator/Lift
Book @ AED 0
Breakfast Included
Excellent4.6

Based on 1002 Ratings and 0 reviews

Cleanliness4.7

Room4.7

Hospitality4.6

(1002 Ratings)

AED 988

+ AED 168 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Wingate Houston near NRG Park/Medical Center

Astrodome | In South Main, Houston (TX), Texas
Room, 1 King Bed, Accessible, Non Smoking (mobility/hearing,tub W Grab Bars)
| Kingbed
Swimming PoolSwimming Pool
GymGym
Elevator/LiftElevator/Lift
Free Cancellation
Book @ AED 0
Breakfast Included
Hurry! only last few rooms left at this price

AED 841

+ AED 185 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Sterling Inn and Suites at Reliant and Medical Center Houston

South Main
King Room
| King Bed(s)
Free Cancellation till 4 hrs before check in
Pay@Hotel
Hurry! only last few rooms left at this price

AED 251

+ AED 43 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Quality Inn & Suites NRG Park - Medical Center

South Main
Standard Room, 2 Queen Beds, Non Smoking
| Queenbed
Free Shuttle ServiceFree Shuttle Service
Swimming PoolSwimming Pool
GymGym
Book @ AED 0
Breakfast Included
Hurry! only last few rooms left at this price

AED 434

+ AED 95 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Scottish Inn and Suites NRG Park/Texas Medical Center - Houston

Astrodome | In South Main, Houston (TX), Texas
King Room
| King Bed(s)
Free ParkingFree Parking
Hurry! only 1 room left at this price

AED 404

+ AED 69 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Motel 6 Houston, TX - Medical Center/NRG Stadium

South Main
Standard Room, 1 King Bed, Accessible, Non Smoking
| Kingbed
Swimming PoolSwimming Pool
Elevator/LiftElevator/Lift
Free ParkingFree Parking
Free Cancellation till 24 hrs before check in
Book @ AED 0
Hurry! only 1 room left at this price
Good3.0

Based on 1001 Ratings and 0 reviews

Location3.8

Cleanliness3.1

Room2.9

Hospitality3.4

(1001 Ratings)

AED 200

AED 167

+ AED 44 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Studio 6 Houston, TX – Medical Center NRG Stadium

South Main
Deluxe Room, 2 Queen Beds, Non Smoking, Kitchenette
| Queenbed
Elevator/LiftElevator/Lift
Free ParkingFree Parking
Free Cancellation till 24 hrs before check in
Book @ AED 0
Average2.9

Based on 121 Ratings and 0 reviews

Cleanliness3

Room2.8

Hospitality3.2

(121 Ratings)

AED 241

AED 202

+ AED 53 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Holiday Inn HOUSTON S - NRG AREA - MED CTR

Astrodome | In South Main, Houston (TX), Texas
Standard Room, 1 King Bed, Accessible (mobil, Tub)
| King Bed
Free Shuttle ServiceFree Shuttle Service
JacuzziJacuzzi
Swimming PoolSwimming Pool
Hurry! only last few rooms left at this price
Very Good3.9

Based on 1002 Ratings and 0 reviews

Cleanliness4

Room3.7

Hospitality3.9

(1002 Ratings)

AED 1,855

+ AED 315 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Candlewood Suites HOUSTON MEDICAL CENTER

South Main
Studio Suite, 1 Queen Bed, Accessible (mobil Tub)
| Queenbed
Free Shuttle ServiceFree Shuttle Service
Swimming PoolSwimming Pool
GymGym
Free Cancellation
Book @ AED 0
Hurry! only last few rooms left at this price
Very Good3.8

Based on 719 Ratings and 0 reviews

Location4

Cleanliness4.1

Room3.9

Value For Money3.8

Hospitality4

(719 Ratings)

AED 624

+ AED 106 taxes & fees

Per Night

Login to Book Now & Pay Later!
hotelImg
default background imagedefault background imagedefault background imagedefault background image

Wyndham Houston near NRG Park/Medical Center

Astrodome | In South Main, Houston (TX), Texas
Room, 2 Double Beds, Non Smoking
| Fullbed
Swimming PoolSwimming Pool
GymGym
Elevator/LiftElevator/Lift
Free Cancellation till 24 hrs before check in
Book @ AED 0
Very Good3.6

Based on 1001 Ratings and 0 reviews

Cleanliness3.7

Room3.3

Hospitality4

(1001 Ratings)

AED 869

+ AED 191 taxes & fees

Per Night

Login to Book Now & Pay Later!

Cheap Hotels in Nearby Cities

Show More

Luxury Hotels in Nearby Cities

Show More

Properties In Houston (TX), Texas

Pay at Hotel in South Main, Houston (TX), Texas

Braeburn

George Bush Park/Eldridge

Southwest Houston

Washington Avenue Coalition / Memorial Park

Houston West

Energy Corridor

Central Business District

Show
Hide

More Deals For You!

More discounts for your Hotels

Get Flat

12% off*

MMTWELCOME

Upto AED 500. Applicable only for First time user


Up to

20% off*

SUPERSAVER

Upto AED 400. Valid on 100,000+ Hotels.


Up to

30% off*

SAVERSUPER

Get Great Discount, Upto AED 500.